the effects of pulsed electric field (pef) on the cell disintegration of sugar beet were studied. field strength (0.5kv/cm to 6kv/cm), pulse number (1 to 100 pulses) and capacity of capacitors (0.5 f to 32 f) were evaluated on degree of cell disintegration and consumed energy in pef treatment. the field conditions of 1 and 2 kv/cm, 8 f with 20 and 10 pulses respectively disintegrated the cel...

objective(s) this study was carried out in order to evaluate the effects of electrochemotherapy, electrical pulses and chemotherapeutic drugs on the killing of cancerous cells and their probable synergistic effects. materials and methods electrochemotherapy treatments conducted on mcf-7 cell line derived from human breast adenocarcinoma tumor using four chemotherapeutic drugs including bleomyci...

Introduction: Irreversible electroporation (IRE) is a process in which the membrane of the cancer cells are irreversibly damaged with the use of high-intensity electric pulses, which in turn leads to cell death. The IRE is a non-thermal way to ablate the cancer cells. This process relies on the distribution of the electric field, which affects the pulse amplitude, width, and electrical conducti...

the effect of pulse electric field on mass transfer in sugar beet cossettes with different thicknesses were investigated and compared with traditional thermal processing. two kinds of sugar beet cossettes 3±0.5 cm and 2±0.5 thicknesses with 3–5 cm long subjected to pulse electric field (3kv, 8 µf, and 20 pulse) and compared with heat treated samples (80ºc for15 minutes) as conventional thermal ...

introduction: electroporation is a practical technique used to transport the molecules across the cell membrane. the utilization of fluorescent molecules is the method widely used to evaluate the electropermeability of cell membrane as a result of pulse application. it is also possible to use mathematical methods to predict the changes caused in cell electropermeability as a result of the chang...

Abstract – In this paper, the effect of applied electric field on the damage due to partial discharges activity into the surroundings dielectrics of a narrow channel encapsulated within the volume of a dielectric material is evaluated using a kinetic model based on Particle in Cell - Monte Carlo Collision (PIC-MCC) model. After application of an electric field across a dielectric material which...

Electric discharge drill machine (EDDM) is a spark erosion process to produce micro-holes in conductive materials. This process is widely used in aerospace, medical, dental and automobile industries. As for the performance evaluation of the electric discharge drilling machine, it is very necessary to study the process parameters of machine tool. In this research paper, a brass rod 2 mm diameter...

A propagation of pulse generated by an electric dipole is studied. A general formula for the electric field, which is uniformly valid for large distance and time, is presented. Fourier transform, stationary phase and simple contour integration methods are applied. 1. CURRENT PULSE AND FOURIER TRANSFORM Electric dipole is excited by a current I(t) = I0f(t) where f(t) is a pulse. The Fourier tran...

Gene electrotransfer is a physical method used to deliver genes into the cells by application of short and intense electric pulses, which cause destabilization of cell membrane, making it permeable to small molecules and allows transfer of large molecules such as DNA. It represents an alternative to viral vectors, due to its safety, efficacy and ease of application. For gene electrotransfer dif...

Controlled permeability can be conferred to cell membranes by exposing cells to a microsecond electric pulse of sufficient intensity (electroporation). By constructing a fluorescence microimaging system with a submicrosecond time resolution we have been able to resolve temporally and spatially the events in a single cell under a microsecond electric pulse. An enormous membrane conductance, corr...